<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>13</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Francisco J. Romero-Campero</style></author><author><style face="normal" font="default" size="100%">Jamie Twycross</style></author><author><style face="normal" font="default" size="100%">Miguel Cámara</style></author><author><style face="normal" font="default" size="100%">Malcolm Bennett</style></author><author><style face="normal" font="default" size="100%">Marian Gheorghe</style></author><author><style face="normal" font="default" size="100%">Natalio Krasnogor</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Modular Assembly of Cell Systems Biology Models Using P systems</style></title><secondary-title><style face="normal" font="default" size="100%">International Journal of Foundations of Computer Science</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Modular Biology</style></keyword><keyword><style  face="normal" font="default" size="100%">P systems</style></keyword><keyword><style  face="normal" font="default" size="100%">Synthetic Biology</style></keyword><keyword><style  face="normal" font="default" size="100%">Systems Biology</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2009</style></year><pub-dates><date><style  face="normal" font="default" size="100%">01/2009</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.cs.nott.ac.uk/~nxk/PAPERS/IJFCS_Nottingham.pdf</style></url></web-urls></urls><publisher><style face="normal" font="default" size="100%">World Scientific</style></publisher><pub-location><style face="normal" font="default" size="100%">London, U.K.</style></pub-location><volume><style face="normal" font="default" size="100%">20</style></volume><pages><style face="normal" font="default" size="100%">427-442</style></pages><abstract><style face="normal" font="default" size="100%">In this paper we propose an extension of a systems/synthetic biology modelling
framework based on P systems that explicitly includes modularity. Modularisation in
cellular systems can be produced by chemical specificity, spatial localisation and/or temporal
modulation within cellular compartments. The first two of these modularisation
features, the focus of this paper, can be easily specified and analysed in P systems using
sets of rewriting rules to describe chemical specificity and membranes to represent spatial
localisation. Our methodology enables the assembly of cell systems biology models by
combining modules which represent functional subsystems. A case study consisting of a
bacterial colony system is presented to illustrate our approach.</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><custom1><style face="normal" font="default" size="100%">0.512</style></custom1><custom2><style face="normal" font="default" size="100%">81/92 - Q4</style></custom2></record></records></xml>