Modeling Logic Gene Networks by Means of Probabilistic Dynamic P Systems

TitleModeling Logic Gene Networks by Means of Probabilistic Dynamic P Systems
Publication TypeJournal Papers
Year of Publication2013
AuthorsValencia-Cabrera, L., García-Quismondo M., Pérez-Jiménez M. J., Su Y., Yu H., & Pan L.
Journal TitleInternational Journal of Unconventional Computing
PublisherOld City Publishing Inc.
Place PublishedPhiladelphia, USA
Date Published10/2013

Gene regulatory networks are useful models for biologists to understand the interactions among genes in living organisms. In this work, we consider a special class of gene regulatory networks, called logical networks, where the “links” among genes are inferred by logic analysis of phylogenetic profiles. We provide a formalization of logic networks, and introduce a membrane computing model for reconstructing logical networks and reproducing their dynamics. An example logical network is simulated by using software P-Lingua and MeCoSim. The simulation result shows that membrane computing is a versatile framework for modeling different biological scenarios.

Keywordsgene, genetic network, logic network, Membrane computing, P system, System biology
Impact Factor



82/100 - Q4

ISSN Number1548-7199
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