Title | Modeling Logic Gene Networks by Means of Probabilistic Dynamic P Systems |
Publication Type | Journal Papers |
Year of Publication | 2013 |
Authors | Valencia-Cabrera, L., García-Quismondo M., Pérez-Jiménez M. J., Su Y., Yu H., & Pan L. |
Journal Title | International Journal of Unconventional Computing |
Publisher | Old City Publishing Inc. |
Place Published | Philadelphia, USA |
Volume | 9 |
Pages | 445-464 |
Date Published | 10/2013 |
Abstract | Gene regulatory networks are useful models for biologists to understand the interactions among genes in living organisms. In this work, we consider a special class of gene regulatory networks, called logical networks, where the “links” among genes are inferred by logic analysis of phylogenetic profiles. We provide a formalization of logic networks, and introduce a membrane computing model for reconstructing logical networks and reproducing their dynamics. An example logical network is simulated by using software P-Lingua and MeCoSim. The simulation result shows that membrane computing is a versatile framework for modeling different biological scenarios. |
Keywords | gene, genetic network, logic network, Membrane computing, P system, System biology |
URL | http://www.oldcitypublishing.com/IJUC/IJUCcontents/IJUCv9n5-6contents.html |
Issue | 5-6 |
Impact Factor | 0.431 |
Ranking | 82/100 - Q4 |
ISSN Number | 1548-7199 |
Full Text | Abstract: http://www.oldcitypublishing.com/IJUC/IJUCabstracts/IJUC9.5-6abstracts/I... |